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László Lakatos MD | szakcikk |

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IBD-related Malignancies Observed in 2015–2019

Szerző: Ágnes Milassin MD; Mariann Rutka MD; Klaudia Farkas MD; Mark Marcus MD; Renáta Bor MD; Kata Judit Szántó MD; Ferenc Nagy MD; Zoltán Szepes MD; Anna Fábián MD; Anita Bálint MD; Tamás Molnár MD¹ Mónika Szűcs MD² László Lakatos MD; Zsuzsanna Erdélyi MD³ László Szegedi MD⁴ Eszter Schäfer MD⁵ Attila Zaránd MD⁶
¹Department of Medicine, University of Szeged, Albert Szent-Györgyi Faculty of Medicine and Health Center, Hungary
²Department of Medical Physics and Informatics, University of Szeged, Albert Szent-Györgyi Medical School, Faculty of Science and Informatics, Hungary
³Department of Internal Medicine, Csolnoky Ferenc Regional Hospital, Veszprém, Hungary
⁴First Department of Internal Medicine, András Jósa Teaching Hospital, Nyíregyháza, Hungary
⁵Military Hospital Medical Center, Hungarian Defense Forces, Budapest, Hungary
⁶First Department of Surgery, Semmelweis University, Budapest, Hungary

Introduction: Patients with inflammatory bowel disease (IBD) have an increased risk to develop malignant neoplasms. Neither the exact mechanism, nor the frequency of different malignancies is completely clear. Our aim was to assess the IBD associated malignancies, to collect clinical and mortality data and to analyse possible risk factors.
Methods: Data on malignancies developed between January 2015 and May 2019 in Hungarian IBD patients ...

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Szerző: Kata Szántó MD*, Mariann Rutka MD*, Ágnes Milassin MD, Klaudia Farkas MD PhD, Anna Fabián MD, Renáta Bor MD, Zoltán Szepes MD, Tamás Molnár MD PhD¹ Tibor Nyári MD PhD, András Lajos Szijártó PhD² Prof István Rácz MD, Andrea Szabó MD, Valéria Kovács MD³ Árpád Patai MD PhD, Krisztina Sarang MD⁴ Lilla Lakner MD PhD, László Lakatos MD PhD⁵ Imre Szabó MD⁶ Zsolt Szinku MD⁷ Ágnes Salamon MD⁸ Károly Palatka MD⁹ Gábor Horváth MD¹⁰ Róbert Sike MD¹¹ Gábor Tamás Tóth MD¹²
¹1st Department of Medicine, University of Szeged, Szeged
²Department of Medical Physics and Informatics, University of Szeged, Szeged
³Aladar Petz County Teaching Hospital, Győr
⁴Markusovszky University Teaching Hospital, Szombathely
⁵Csolnoky Ferenc Veszprém County Hospital, Veszprém
⁶1st Department of Internal Medicine, University of Pécs, Pécs
⁷Kaposi Mór Teaching Hospital, Kaposvár
⁸Tolna County Balassa Janos Hospital, Szekszárd
⁹2nd Department of Medicine University of Debrecen, Debrecen
¹⁰Borsod-Abaúj-Zemplén Megyei Központi Kórház és Egyetemi Oktatókórház, Miskolc
¹¹Saint Margit Hospital, Budapest
¹²Saint John Hospital, Budapest

Inflammatory bowel diseases have a huge impact on the quality of life and workability. The fully human anti-TNF-alpha, adalimumab provides great opportunity to use biological therapy at home, application of the prefilled syringe might be difficult for some. The aim of this study was to evaluate patients’ opinion about the newly introduced adalimumab prefilled pen compared to the prefilled syringe. Our questionnaire based survey focused on the ...

Pouch carcinoma following restorative proctocolectomy for ulcerative colitis

Szerző: László Lakatos MD, Zsuzsanna Végh MD, Tünde Pandur MD¹ Erika Ligeti MD² István Moldoványi MD³ Elemer Mohos MD, Csaba Berki MD⁴ Lajos Hornyák MD⁵ István Dobo MD⁶ Zsuzsanna Végh MD, Péter L. Lakatos MD⁷
¹Csolnoky Ferenc Province Hospital, Department of Medicine
²Csolnoky Ferenc Province Hospital, Department of Pathology
³Csolnoky Ferenc Province Hospital, Department of Radiology
⁴Csolnoky Ferenc Province Hospital, Department of Surgery
⁵Department of Oncology, Veszprem, Hungary
⁶Csolnoky Ferenc Province Hospital, Szt. Margit Hospital, Department of Surgery, Budapest, Hungary
⁷Csolnoky Ferenc Province Hospital, Semmelweis University, First Department of Medicine, Budapest, Hungary Correspondence: laklaci@yahoo.com

The risk of colorectal cancer (CRC) is increased in patients with ulcerative colitis (UC). Restorative proctocolectomy with ileal pouch-anal anastomosis (IPAA) is the surgical treatment of choice for patients with UC refractory to medical treatment or with CRC/dyplasia. However, the procedure does not completely abolish the risk for neoplasia. Pouch-related cancers can develop in the pouch and in the anal transitional zone. The most ...

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IBD-related Malignancies Observed in 2015–2019

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Pouch carcinoma following restorative proctocolectomy for ulcerative colitis

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