Somatostatin plays an important role in regulation of neurotransmission and secretion, prevents release of growth hormone, thyroid-stimulating hormone, pancreatic enzymes, gastrointestinal hormones. Somatostatin analogue, octreotide was the first formulation used in clinical practice with a rationale to inhibit secretion of neuropeptides secreted by gastrointestinal neuroendocrine tumour which express somatostatin receptors. Octreotide plays an ...